Search Result
Results for "
pH probes
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W110898
-
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Fluorescent Dye
|
Others
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Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .
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- HY-118155
-
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Fluorescent Dye
|
Others
|
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
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-
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- HY-D1694
-
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Fluorescent Dye
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Others
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LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH. (λex=465 nm, λem=535 nm) .
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-
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- HY-149680
-
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Others
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Others
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CatD-P1is a pH insensitive CatD (Cathepsin D) probe .
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-
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- HY-145576
-
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Others
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Others
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2-Amino-8-oxononanoic acid is an amino acid, incorporation into proteins in E.coli in genetic. 2-Amino-8-oxononanoic acid is efficient in labeling of proteins with different probes with a site-specific manner under a mild condition close to the physiological pH .
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-
-
- HY-W411215
-
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Fluorescent Dye
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Others
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1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .
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-
-
- HY-145576B
-
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Others
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Others
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2-Amino-8-oxononanoic acid (hydrochloride) is the hydrochloride form of 2-Amino-8-oxononanoic acid. 2-Amino-8-oxononanoic acid is an amino acid, incorporation into proteins in E.coli in genetic. 2-Amino-8-oxononanoic acid is efficient in labeling of proteins with different probes with a site-specific manner under a mild condition close to the physiological pH .
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-
-
- HY-D1591
-
|
Fluorescent Dye
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Others
|
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .
|
-
-
- HY-D1457
-
|
Fluorescent Dye
|
Others
|
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
|
-
-
- HY-163146
-
|
Fluorescent Dye
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Cancer
|
TME-HYM (PH Probe) is a novel fluorescent probe based on acidic tumor microenvironment (TME) activation and organic anion transporting polypeptide (OATPs, overexpressed on cancer cells), and can be selective uptaken. TME-HYM (PH Probe) can selectively lit up cancer cells and tumor tissues, offering dual tumor selectivity for precise visualization of tumor mass .
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-
-
- HY-D1094
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SNARF 1
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Fluorescent Dye
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Others
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Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement of intracellular pH .
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- HY-D1093
-
|
Fluorescent Dye
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Others
|
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
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-
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- HY-D2119
-
|
Fluorescent Dye
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Cancer
|
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .
|
-
-
- HY-D1556
-
|
Fluorescent Dye
|
Others
|
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
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-
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- HY-15923
-
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Reactive Oxygen Species
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Others
|
MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
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-
-
- HY-130027
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HKOCl-4
1 Publications Verification
BXY2142
|
Fluorescent Dye
|
Others
|
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
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-
-
- HY-D0050
-
|
Fluorescent Dye
|
Others
|
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester (cDCFDASE) is a fluorescent probe. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester can be used to evaluate the intracellular pH (pHin) of living cells at a medium pH (pHex) .
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-
-
- HY-D0140
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ETH 5294
|
Fluorescent Dye
|
Others
|
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .
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- HY-155717
-
|
Autophagy
Pim
|
Cancer
|
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation .
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-
-
- HY-147104
-
|
Fluorescent Dye
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Others
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Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu 2+-sensitive fluorescence dye .
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-
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- HY-D1482
-
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Fluorescent Dye
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Others
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Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
-
- HY-151544
-
|
Fluorescent Dye
|
Others
|
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .
|
-
-
- HY-15940
-
5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
|
Fluorescent Dye
|
Cancer
|
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
|
-
-
- HY-D1156
-
|
Reactive Oxygen Species
Fluorescent Dye
|
Others
|
HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
-
- HY-D1156A
-
|
Reactive Oxygen Species
Fluorescent Dye
|
Others
|
HKSOX-1m (5/6-mixture) hydrobromide is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
-
- HY-D1688
-
|
Fluorescent Dye
|
Others
|
Flubida-2 is a cell permeable dye which can be hydrolyzed to Fubi-2 by endoesterases in cells (after hydrolysis, Ex=492 nm, Em=517 nm). Flubida-2 can be used to detect pH at a specific site in a cell organelle by directing the probe to where avidin fusion proteins are located .
|
-
-
- HY-124473
-
NapHthafluorescein
|
HIF/HIF Prolyl-Hydroxylase
|
Cancer
|
Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.
Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
|
-
-
- HY-150086
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CF4
|
Fluorescent Dye
|
Others
|
Copper Fluor-4 (CF4) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (Ex: 488 nm) .
|
-
-
- HY-B1422
-
Aminacrine
|
Bacterial
HIV
|
Infection
|
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
-
- HY-143285
-
|
Fluorescent Dye
|
|
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
|
-
-
- HY-B1422S
-
Aminacrine-13C6
|
Bacterial
HIV
Isotope-Labeled Compounds
|
Infection
|
9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-118155
-
|
Fluorescent Dyes/Probes
|
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
|
-
- HY-D1457
-
|
Fluorescent Dyes/Probes
|
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
|
-
- HY-W411215
-
|
Fluorescent Dyes/Probes
|
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .
|
-
- HY-D1591
-
|
Fluorescent Dyes/Probes
|
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .
|
-
- HY-157036
-
|
Fluorescent Dyes/Probes
|
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .
|
-
- HY-D1094
-
SNARF 1
|
Fluorescent Dyes/Probes
|
Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement of intracellular pH .
|
-
- HY-D1093
-
|
Fluorescent Dyes/Probes
|
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
|
-
- HY-D2119
-
|
Fluorescent Dyes/Probes
|
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .
|
-
- HY-D1556
-
|
Fluorescent Dyes/Probes
|
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
|
-
- HY-15923
-
|
Fluorescent Dyes/Probes
|
MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
|
-
- HY-130027
-
HKOCl-4
1 Publications Verification
BXY2142
|
Fluorescent Dyes/Probes
|
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
|
-
- HY-D0140
-
ETH 5294
|
Fluorescent Dyes/Probes
|
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .
|
-
- HY-D1482
-
|
Fluorescent Dyes/Probes
|
Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-151544
-
|
Fluorescent Dyes/Probes
|
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .
|
-
- HY-15940
-
5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
|
Fluorescent Dyes/Probes
|
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
|
-
- HY-D1156
-
|
Fluorescent Dyes/Probes
|
HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
- HY-D1156A
-
|
Fluorescent Dyes/Probes
|
HKSOX-1m (5/6-mixture) hydrobromide is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
- HY-D1688
-
|
Fluorescent Dyes/Probes
|
Flubida-2 is a cell permeable dye which can be hydrolyzed to Fubi-2 by endoesterases in cells (after hydrolysis, Ex=492 nm, Em=517 nm). Flubida-2 can be used to detect pH at a specific site in a cell organelle by directing the probe to where avidin fusion proteins are located .
|
-
- HY-150086
-
CF4
|
Dyes
|
Copper Fluor-4 (CF4) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (Ex: 488 nm) .
|
-
- HY-B1422
-
Aminacrine
|
Fluorescent Dyes/Probes
|
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
- HY-143285
-
|
Fluorescent Dyes/Probes
|
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1422S
-
|
9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-131442
-
Alkyne tyramide; Alk-pH
|
|
Alkynes
Labeling and Fluorescence Imaging
|
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1482
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
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